WDR11

Across TCGA patient cohorts, WDR11 protein abundance is significantly associated with the RNA expression of many other genes, with 15,575 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WDR11-associated genes across cancer lineages are ZNF22, GPR161, and CLEC1A. Each is linked with WDR11 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDR11-to-partner and partner-to-WDR11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR11 versus ZNF22 in GBM, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR11→partner) and Y-score (partner→WDR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF22 →	-0.597	-0.160	<.001	.001	3	4
BRCA	GPR161 →	-0.564	-0.156	.006	.006	3	4
CCRCC	CLEC1A →	-0.717	-0.181	<.001	<.001	3	4
CCRCC	ADGRL4 →	-0.738	-0.161	<.001	<.001	3	4
LSCC	ZDHHC21 →	-0.491	-0.098	<.001	.005	3	4
GBM	GLT1D1 →	-0.714	-0.165	.008	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,575 associations by consensus.

WDR11 vs ZNF22 — GBM

Explore this scatter interactively →