WDR11

Across TCGA cell cohorts, WDR11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,195 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR11-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Cytosolic transport, and Phosphatidylinositol biosynthetic process. Each is linked with WDR11 in more than 15 cancer types. Because this analysis shows association rather than direction, both WDR11-to-partner and partner-to-WDR11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by WDR11-low versus WDR11-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR11→partner) and Y-score (partner→WDR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Viral translational termination-reinitiation →	+0.100	+1.049	<.001	<.001	3	16
OESOPHAGUS	Cytosolic transport →	+0.061	+0.503	.002	.009	3	14
BONE	Phosphatidylinositol biosynthetic process →	+0.068	+0.864	<.001	<.001	3	13
LUNG_SCLC	Golgi organization →	+0.055	+0.626	<.001	.001	3	13
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.085	+0.551	.002	.003	3	13
LUNG_SCLC	Target-directed miRNA degradation →	+0.114	+0.711	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,195 associations by consensus.

Viral translational termination-reinitiation by WDR11 expression — LUNG_SCLC

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