WDR11

Across TCGA cell cohorts, WDR11 mutation is significantly associated with the RNA expression of many other genes, with 391 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR11-associated genes across cancer lineages are TRMU, BCAS2, and RAP1GDS1. Each is linked with WDR11 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR11-to-partner and partner-to-WDR11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMU grouped by WDR11-low versus WDR11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR11→partner) and Y-score (partner→WDR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRMU →	+0.658	+3.364	<.001	.002	3	2
LARGE_INTESTINE	BCAS2 →	+0.727	+3.364	<.001	.002	3	2
LARGE_INTESTINE	RAP1GDS1 →	+0.651	+3.364	<.001	.002	3	2
LARGE_INTESTINE	LARP1B →	+0.810	+3.364	<.001	.002	3	2
LARGE_INTESTINE	PRSS53 →	+0.600	+3.364	<.001	.002	3	2
LARGE_INTESTINE	ZBTB41 →	+0.500	+3.364	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

TRMU by WDR11 expression — LARGE_INTESTINE

Explore this box plot interactively →