WDFY4

Across TCGA patient cohorts, WDFY4 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,546 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDFY4-associated proteins across cancer lineages are WAS, WIPF1, and COTL1. Each is linked with WDFY4 in more than 9 cancer types. Because this analysis shows association rather than direction, both WDFY4-to-partner and partner-to-WDFY4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY4 versus WAS in GBM, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY4→partner) and Y-score (partner→WDFY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.736	+1.106	<.001	<.001	3	10
OV	WIPF1 →	+0.653	+0.945	<.001	<.001	3	10
HNSC	COTL1 →	+0.656	+1.045	<.001	<.001	3	10
GBM	DOCK2 →	+0.832	+1.126	<.001	<.001	3	10
GBM	DOCK8 →	+0.702	+1.155	<.001	<.001	3	10
HNSC	EVL →	+0.880	+1.222	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,546 associations by consensus.

WDFY4 vs WAS — GBM

Explore this scatter interactively →