WDFY4

Across TCGA cell cohorts, WDFY4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDFY4-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Regulation of aggrephagy, and Cellular response to insulin stimulus. Each is linked with WDFY4 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDFY4-to-partner and partner-to-WDFY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by WDFY4-low versus WDFY4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY4→partner) and Y-score (partner→WDFY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of protein localization to organelle →	+0.033	+0.045	<.001	.006	3	7
BLOOD_Lymphoma	Regulation of aggrephagy →	+0.083	+2.221	.001	.001	3	6
PANCREAS	Cellular response to insulin stimulus →	+0.052	+0.051	<.001	.003	3	6
OVARY	Purine nucleoside triphosphate metabolic process →	+0.080	+0.094	<.001	.001	3	6
OVARY	Purine ribonucleoside triphosphate metabolic process →	+0.078	+0.099	<.001	<.001	3	6
OVARY	Negative regulation of myoblast fusion →	+0.091	+0.107	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,102 associations by consensus.

Establishment of protein localization to organelle by WDFY4 expression — URINARY_TRACT

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