WDFY3-AS2

Across TCGA pan-cancer cohorts, WDFY3-AS2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated WDFY3-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher WDFY3-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WDFY3-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.

KIRC, UVM, and LGG are the cancer types where WDFY3-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.722	0.535	<.001	122	view →
UVM	DFS	Tertile	All	0.754	0.372	<.001	64	view →
LGG	DFS	Median	All	0.821	0.655	<.001	51	view →
ESCA	OS	Median	All	0.637	0.387	.001	33	view →
MESO	OS	Median	All	0.485	0.294	.011	22	view →
STAD	OS	Quartile	All	0.276	0.518	.015	14	view →
HNSC	OS	Quartile	II,III,IV	0.330	0.501	.016	14	view →
LUAD	DFS	Median	III,IV	0.255	0.555	.020	12	view →
PAAD	OS	Median	All	0.443	0.261	.014	12	view →
BRCA	DFS	Tertile	III,IV	0.936	0.808	.008	12	view →
KIRP	OS	Tertile	All	0.882	0.493	.007	12	view →
SARC	DFS	Median	All	0.713	0.550	.005	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

WDFY3-AS2–KIRC (OS)

Open the KIRC breakdown →