WDCP

Across TCGA patient cohorts, WDCP protein abundance is significantly associated with the RNA expression of many other genes, with 8,545 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDCP-associated genes across cancer lineages are CENPA, CENPO, and RRM2. Each is linked with WDCP in more than 5 cancer types. Because this analysis shows association rather than direction, both WDCP-to-partner and partner-to-WDCP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDCP versus CENPA in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDCP→partner) and Y-score (partner→WDCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CENPA →	+0.933	+0.342	<.001	<.001	3	6
HNSC	CENPO →	+0.715	+0.539	<.001	<.001	3	6
GBM	RRM2 →	+1.057	+0.358	<.001	<.001	3	6
UCEC	PRR11 →	+0.856	+0.313	.003	<.001	3	6
GBM	TRIP13 →	+0.908	+0.381	<.001	<.001	3	6
GBM	GINS1 →	+0.797	+0.285	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,545 associations by consensus.

WDCP vs CENPA — GBM

Explore this scatter interactively →