WBP4

Across TCGA patient cohorts, WBP4 protein abundance is significantly associated with the RNA expression of many other genes, with 16,263 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WBP4-associated genes across cancer lineages are MRPS31, RFC3, and NUDT15. Each is linked with WBP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both WBP4-to-partner and partner-to-WBP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WBP4 versus MRPS31 in GBM, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP4→partner) and Y-score (partner→WBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MRPS31 →	+0.519	+0.408	<.001	<.001	3	6
GBM	RFC3 →	+0.913	+0.406	<.001	<.001	3	6
UCEC	NUDT15 →	+0.813	+0.295	<.001	<.001	3	6
UCEC	ESD →	+0.872	+0.242	.004	.001	3	6
OV	SAP18 →	+0.451	+0.278	<.001	.004	3	6
LSCC	NUFIP1 →	+0.578	+0.390	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,263 associations by consensus.

WBP4 vs MRPS31 — GBM

Explore this scatter interactively →