WBP4

Across TCGA patient cohorts, WBP4 mutation is significantly associated with the RNA expression of many other genes, with 1,581 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP4-associated genes across cancer lineages are SEPTIN14P17, RNA5SP361, and SNORA10B. Each is linked with WBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP4-to-partner and partner-to-WBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN14P17 grouped by WBP4-low versus WBP4-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP4→partner) and Y-score (partner→WBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN14P17 →	+0.438	+5.575	<.001	.004	3	2
BRCA	RNA5SP361 →	+0.313	+6.571	<.001	.001	3	2
BRCA	SNORA10B →	+0.266	+5.441	<.001	.005	3	2
BRCA	MTCYBP8 →	+0.097	+6.639	<.001	.001	3	2
BRCA	NDUFA5P5 →	+0.176	+6.866	<.001	<.001	3	2
BRCA	RNU6-1236P →	+0.195	+8.057	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,581 associations by consensus.

SEPTIN14P17 by WBP4 expression — BRCA

Explore this box plot interactively →