WBP4

Across TCGA cell cohorts, WBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,467 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WBP4-associated GO terms across cancer lineages are Mitochondrial translational termination, Sister chromatid biorientation, and Formaldehyde catabolic process. Each is linked with WBP4 in more than 14 cancer types. Because this analysis shows association rather than direction, both WBP4-to-partner and partner-to-WBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translational termination grouped by WBP4-low versus WBP4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP4→partner) and Y-score (partner→WBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial translational termination →	+0.118	+0.647	<.001	.005	3	15
LARGE_INTESTINE	Sister chromatid biorientation →	+0.123	+0.546	.002	.004	3	13
UPPER_AERODIGESTIVE_TRACT	Formaldehyde catabolic process →	+0.109	+0.732	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, centromeric region →	+0.148	+0.713	.001	.001	3	12
LUNG_NSCLC_LUAD	Positive regulation of mitotic sister chromatid separation →	+0.104	+0.729	<.001	<.001	3	12
CNS	Nucleotide-excision repair, DNA gap filling →	+0.082	+0.500	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,467 associations by consensus.

Mitochondrial translational termination by WBP4 expression — BONE

Explore this box plot interactively →