WBP4

Across TCGA cell cohorts, WBP4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible WBP4-associated genes across cancer lineages are OR51D1 and LRIT2. Each is linked with WBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP4-to-partner and partner-to-WBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51D1 grouped by WBP4-low versus WBP4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP4→partner) and Y-score (partner→WBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR51D1 →	+0.070	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	LRIT2 →	+0.029	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR51D1 by WBP4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →