WBP2

Across TCGA patient cohorts, WBP2 mutation is significantly associated with the RNA expression of many other genes, with 584 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP2-associated genes across cancer lineages are LINC00351, LINC01815, and MTND2P8. Each is linked with WBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP2-to-partner and partner-to-WBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00351 grouped by WBP2-low versus WBP2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP2→partner) and Y-score (partner→WBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00351 →	+0.162	+5.201	<.001	.007	3	2
CESC	LINC01815 →	+0.887	+5.103	<.001	.008	3	1
CESC	MTND2P8 →	+0.077	+5.418	<.001	.005	3	1
CESC	HMGB3P12 →	+0.143	+6.144	<.001	.001	3	1
CESC	RNU6-506P →	+0.429	+6.144	<.001	.001	3	1
CESC	VN1R78P →	+0.091	+5.306	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 584 associations by consensus.

LINC00351 by WBP2 expression — CESC

Explore this box plot interactively →