WBP1L

Across TCGA patient cohorts, WBP1L protein abundance is significantly associated with the RNA expression of many other genes, with 2,260 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WBP1L-associated genes across cancer lineages are HTR2A, RUSC1, and RNU6-1091P. Each is linked with WBP1L in more than 2 cancer types. Because this analysis shows association rather than direction, both WBP1L-to-partner and partner-to-WBP1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WBP1L versus HTR2A in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP1L→partner) and Y-score (partner→WBP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HTR2A →	+1.184	+0.370	<.001	<.001	3	3
HNSC	RUSC1 →	+1.303	+0.929	.002	<.001	3	2
HNSC	RNU6-1091P →	-2.903	-0.790	.002	.009	3	2
HNSC	LINC01656 →	-0.873	-0.703	<.001	.001	3	2
HNSC	COX7BP2 →	-1.761	-0.628	.003	<.001	3	2
HNSC	ADAMTS9-AS1 →	-1.642	-0.628	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,260 associations by consensus.

WBP1L vs HTR2A — GBM

Explore this scatter interactively →