WBP1L

Across TCGA cell cohorts, WBP1L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WBP1L-associated genes across cancer lineages are CXorf51A, CNBD1, and OR2B3. Each is linked with WBP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP1L-to-partner and partner-to-WBP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51A grouped by WBP1L-low versus WBP1L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP1L→partner) and Y-score (partner→WBP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CXorf51A →	+0.076	+4.887	<.001	.009	3	1
LARGE_INTESTINE	CNBD1 →	+0.576	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR2B3 →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	POTEB2 →	+0.012	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CXorf51A by WBP1L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →