WBP11

Across TCGA cell cohorts, WBP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,098 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WBP11-associated GO terms across cancer lineages are Positive regulation of cytokinesis, Mitotic spindle elongation, and Meiotic chromosome condensation. Each is linked with WBP11 in more than 17 cancer types. Because this analysis shows association rather than direction, both WBP11-to-partner and partner-to-WBP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytokinesis grouped by WBP11-low versus WBP11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP11→partner) and Y-score (partner→WBP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cytokinesis →	+0.147	+0.878	.002	<.001	3	18
BONE	Mitotic spindle elongation →	+0.315	+0.796	.004	.002	3	17
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.195	+0.813	.001	.003	3	17
BONE	Mitotic spindle midzone assembly →	+0.315	+0.796	.004	.002	3	17
BONE	DNA-templated DNA replication →	+0.168	+1.094	<.001	<.001	3	17
BONE	Heterochromatin organization →	+0.107	+0.890	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,098 associations by consensus.

Positive regulation of cytokinesis by WBP11 expression — BONE

Explore this box plot interactively →