WASIR2

Across TCGA patient cohorts, WASIR2 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASIR2-associated genes across cancer lineages are RNU6-1067P, RNU1-84P, and RNU4-45P. Each is linked with WASIR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASIR2-to-partner and partner-to-WASIR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1067P grouped by WASIR2-low versus WASIR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASIR2→partner) and Y-score (partner→WASIR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1067P →	+0.444	+3.453	.001	.009	3	2
COAD	RNU1-84P →	+1.267	+7.741	<.001	.009	3	2
COAD	RNU4-45P →	+0.538	+7.741	<.001	.009	3	2
UCEC	HMX3 →	+0.958	+3.859	.001	.004	3	1
UCEC	RNU6-79P →	+0.490	+3.982	.002	.003	3	1
UCEC	RNU6-354P →	+0.393	+3.638	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

RNU6-1067P by WASIR2 expression — UCEC

Explore this box plot interactively →