WASHC3

Across TCGA patient cohorts, WASHC3 mutation is significantly associated with the RNA expression of many other genes, with 622 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASHC3-associated genes across cancer lineages are RNU6-1305P, CENPNP1, and RNU6-13P. Each is linked with WASHC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASHC3-to-partner and partner-to-WASHC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1305P grouped by WASHC3-low versus WASHC3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC3→partner) and Y-score (partner→WASHC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-1305P →	+0.329	+4.758	<.001	.006	3	2
LIHC	CENPNP1 →	+0.037	+4.822	.007	.003	3	2
UCEC	RNU6-13P →	+0.368	+2.706	<.001	.003	3	2
LIHC	HIKESHIP3 →	+0.086	+4.544	<.001	.009	3	1
LIHC	VPS35P1 →	+0.028	+4.822	<.001	.003	3	1
LIHC	MIR4267 →	+0.305	+7.503	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 622 associations by consensus.

RNU6-1305P by WASHC3 expression — LIHC

Explore this box plot interactively →