WASHC2C

Across TCGA patient cohorts, WASHC2C mutation is significantly associated with the RNA expression of many other genes, with 3,629 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASHC2C-associated genes across cancer lineages are TMEM120B, TFIP11, and ATP6V1E1. Each is linked with WASHC2C in more than 3 cancer types. Because this analysis shows association rather than direction, both WASHC2C-to-partner and partner-to-WASHC2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM120B grouped by WASHC2C-low versus WASHC2C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC2C→partner) and Y-score (partner→WASHC2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM120B →	+0.239	+2.296	.006	<.001	3	4
SKCM	TFIP11 →	+0.456	+3.379	.007	.004	3	3
SKCM	ATP6V1E1 →	+0.488	+3.378	.002	.004	3	3
LUAD	SLC17A5 →	+0.552	+3.374	.005	.004	3	3
LUAD	RNU5A-4P →	+0.270	+2.842	.002	.002	3	3
UCEC	GUF1 →	+0.526	+1.595	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,629 associations by consensus.

TMEM120B by WASHC2C expression — UCEC

Explore this box plot interactively →