WASHC2C

Across TCGA cell cohorts, WASHC2C mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASHC2C-associated genes across cancer lineages are CT45A7, F9, and IL36A. Each is linked with WASHC2C in more than 1 cancer types. Because this analysis shows association rather than direction, both WASHC2C-to-partner and partner-to-WASHC2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT45A7 grouped by WASHC2C-low versus WASHC2C-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC2C→partner) and Y-score (partner→WASHC2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CT45A7 →	+0.042	+4.930	<.001	.008	3	1
LUNG_SCLC	F9 →	+0.036	+5.643	<.001	.002	3	1
LUNG_SCLC	IL36A →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	OR7G3 →	+0.063	+5.643	<.001	.002	3	1
LUNG_SCLC	FFAR3 →	+0.058	+5.029	<.001	.006	3	1
LUNG_SCLC	FAM25A →	+0.186	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CT45A7 by WASHC2C expression — SOFT_TISSUE

Explore this box plot interactively →