WASF3

Across TCGA pan-cancer cohorts, WASF3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WASF3 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher WASF3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WASF3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where WASF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	II,III,IV	0.508	0.890	.011	21	view →
PDAC	DFS	Median	III,IV	0.122	0.984	.038	6	view →
LUAD	OS	Tertile	II,III,IV	0.848	0.321	.015	6	view →
CCRCC	DFS	Tertile	II,III,IV	0.494	1.000	.040	2	view →
UCEC	DFS	Tertile	All	0.830	0.948	.035	2	view →
GBM	OS	Quartile	All	0.903	0.794	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WASF3–LSCC (DFS)

Open the LSCC breakdown →