WASF1

Across TCGA pan-cancer cohorts, WASF1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated WASF1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WASF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated WASF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where WASF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	0.887	0.198	.024	12	view →
PDAC	DFS	Median	III,IV	0.173	0.892	.006	10	view →
LSCC	OS	Tertile	III,IV	0.512	0.918	.013	8	view →
OV	DFS	Median	All	0.852	1.000	.031	4	view →
UCEC	DFS	Median	III,IV	0.904	0.445	.037	4	view →
LUAD	OS	Median	All	0.880	0.610	.039	2	view →
GBM	DFS	Quartile	All	0.856	0.629	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

WASF1–CCRCC (DFS)

Open the CCRCC breakdown →