Across TCGA patient cohorts, WARS2-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,720 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WARS2-IT1-associated proteins across cancer lineages are SORBS3, MICALL1, and VAMP8. Each is linked with WARS2-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both WARS2-IT1-to-partner and partner-to-WARS2-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WARS2-IT1→partner) and Y-score (partner→WARS2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SORBS3 →	+0.405	+0.314	<.001	<.001	3	6
BRCA	MICALL1 →	-0.388	-0.191	<.001	.002	2	6
GBM	VAMP8 →	-0.419	-0.468	.004	.001	3	5
LSCC	RSBN1 →	+0.294	+0.499	<.001	<.001	3	4
PDAC	CROCC_S512 →	+0.643	+0.322	<.001	<.001	3	4
CCRCC	HDGFL3 →	+0.429	+0.266	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,720 associations by consensus.

Exploration

WARS2-IT1 survival (RNA) · tumor vs normal (RNA) · all WARS2-IT1 data types