WAPL

Across TCGA patient cohorts, WAPL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,702 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WAPL-associated proteins across cancer lineages are VPS26A, NHLRC2, and SLK. Each is linked with WAPL in more than 4 cancer types. Because this analysis shows association rather than direction, both WAPL-to-partner and partner-to-WAPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WAPL versus VPS26A in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WAPL→partner) and Y-score (partner→WAPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VPS26A →	+0.208	+0.263	.001	<.001	3	5
BRCA	NHLRC2 →	+0.244	+0.446	<.001	.001	3	5
BRCA	SLK →	+0.324	+0.553	<.001	<.001	3	5
UCEC	TIAL1 →	+0.237	+0.478	<.001	.001	3	5
GBM	CTBP2 →	+0.388	+0.247	<.001	.004	3	5
PDAC	SNRPD3 →	+0.258	+0.188	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,702 associations by consensus.

WAPL vs VPS26A — PDAC

Explore this scatter interactively →