VXN

Across TCGA patient cohorts, VXN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,999 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VXN-associated proteins across cancer lineages are VCPIP1, NBEAL1, and HSF1. Each is linked with VXN in more than 3 cancer types. Because this analysis shows association rather than direction, both VXN-to-partner and partner-to-VXN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VXN versus VCPIP1 in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VXN→partner) and Y-score (partner→VXN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VCPIP1 →	+0.248	+0.303	<.001	<.001	3	4
BRCA	NBEAL1 →	-0.198	-0.269	.005	.005	3	3
BRCA	HSF1 →	+0.279	+0.281	<.001	<.001	3	3
GBM	IGF2R →	-0.310	-0.503	<.001	<.001	3	3
GBM	FHOD1 →	-0.358	-0.634	<.001	<.001	3	3
COAD	UNK →	+0.214	+0.023	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,999 associations by consensus.

VXN vs VCPIP1 — BRCA

Explore this scatter interactively →