VXN

Across TCGA cell cohorts, VXN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,497 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VXN-associated GO terms across cancer lineages are PML body organization, Terpenoid catabolic process, and Leukotriene catabolic process. Each is linked with VXN in more than 9 cancer types. Because this analysis shows association rather than direction, both VXN-to-partner and partner-to-VXN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by VXN-low versus VXN-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VXN→partner) and Y-score (partner→VXN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PML body organization →	+0.194	+0.455	<.001	.003	3	10
LUNG_NSCLC_LUSC	Terpenoid catabolic process →	-1.534	-0.637	<.001	.005	3	9
LUNG_NSCLC_LUSC	Leukotriene catabolic process →	-1.871	-0.661	<.001	.004	3	9
BONE	Regulation of hippo signaling →	+0.078	+0.551	.002	<.001	3	9
LUNG_NSCLC_LUSC	Isoprenoid catabolic process →	-1.553	-0.637	<.001	.005	3	9
LIVER	Negative regulation of dendritic cell apoptotic process →	+1.605	+0.790	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,497 associations by consensus.

PML body organization by VXN expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →