VWDE

Across TCGA patient cohorts, VWDE protein abundance is significantly associated with the RNA expression of many other genes, with 566 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible VWDE-associated genes across cancer lineages are MYOM1, PEX12, and CWH43. Each is linked with VWDE in more than 1 cancer types. Because this analysis shows association rather than direction, both VWDE-to-partner and partner-to-VWDE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWDE versus MYOM1 in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWDE→partner) and Y-score (partner→VWDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYOM1 →	-0.734	-1.020	.002	.004	3	1
UCEC	PEX12 →	-0.409	-1.057	.006	.001	3	1
UCEC	CWH43 →	-1.664	-1.217	.004	.005	3	1
UCEC	NT5DC3 →	-0.613	-1.223	.004	<.001	3	1
UCEC	RRAS →	-0.844	-1.178	<.001	.005	3	1
UCEC	NPHP1 →	-0.866	-1.188	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

VWDE vs MYOM1 — UCEC

Explore this scatter interactively →