VWDE

Across TCGA cell cohorts, VWDE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,915 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VWDE-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with VWDE in more than 12 cancer types. Because this analysis shows association rather than direction, both VWDE-to-partner and partner-to-VWDE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by VWDE-low versus VWDE-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWDE→partner) and Y-score (partner→VWDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.087	+0.968	.001	.007	3	13
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+1.136	<.001	.008	3	13
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.103	+1.403	<.001	<.001	2	13
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.404	<.001	<.001	2	13
STOMACH	Cytoplasmic translation →	+0.094	+1.713	.002	<.001	3	11
OESOPHAGUS	Oxidative phosphorylation →	+0.095	+1.048	.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,915 associations by consensus.

Regulation of myoblast fusion by VWDE expression — OVARY

Explore this box plot interactively →