VWCE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VWCE RNA expression is significantly associated with the protein abundance of many other proteins, with 7,297 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VWCE-associated proteins across cancer lineages are C4BPB, CD248, and DBN1. Each is linked with VWCE in more than 2 cancer types. Because this analysis shows association rather than direction, both VWCE-to-partner and partner-to-VWCE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWCE versus C4BPB in COAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VWCE→partner) and Y-score (partner→VWCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADC4BPB →+0.756+0.242<.001.00133
UCECCD248 →+0.489+0.583.001.00333
COADDBN1 →+0.340+0.269<.001.00633
PDACDBN1_S337 →+0.496+0.115<.001.00733
LSCCKIAA1522_S545 →-0.871-0.433<.001.00133
UCECARCN1 →-0.179-0.757.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,297 associations by consensus.

VWCE vs C4BPB — COAD

Per-sample scatter of VWCE vs C4BPB in COAD (Pearson r = 0.30).

Explore this scatter interactively →

Exploration