VWA8

Across TCGA cell cohorts, VWA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,443 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VWA8-associated GO terms across cancer lineages are Malate metabolic process, Sister chromatid biorientation, and Copper ion export. Each is linked with VWA8 in more than 14 cancer types. Because this analysis shows association rather than direction, both VWA8-to-partner and partner-to-VWA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Malate metabolic process grouped by VWA8-low versus VWA8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA8→partner) and Y-score (partner→VWA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Malate metabolic process →	+0.143	+0.683	.002	<.001	3	15
LARGE_INTESTINE	Sister chromatid biorientation →	+0.125	+0.702	.001	.005	2	14
LARGE_INTESTINE	Copper ion export →	-0.192	-0.867	<.001	<.001	3	12
CNS	Ribosomal protein import into nucleus →	+0.089	+0.558	<.001	<.001	3	11
LUNG_SCLC	Retrograde transport, vesicle recycling within Golgi →	+0.118	+0.643	<.001	<.001	3	11
STOMACH	Symbiont-mediated disruption of host cell PML body →	+0.106	+0.871	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,443 associations by consensus.

Malate metabolic process by VWA8 expression — LIVER

Explore this box plot interactively →