VWA8-AS1

Across TCGA pan-cancer cohorts, VWA8-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated VWA8-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher VWA8-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated VWA8-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

UCS, HNSC, and UVM are the cancer types where VWA8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.564	0.188	.003	56	view →
HNSC	DFS	Median	IV	0.761	0.573	.003	46	view →
UVM	OS	Quartile	II,III,IV	0.847	0.565	.011	45	view →
READ	OS	Median	II,III,IV	0.978	0.846	.003	41	view →
THCA	OS	Median	All	0.962	1.000	.008	38	view →
LGG	DFS	Median	All	0.478	0.307	<.001	36	view →
ACC	DFS	Median	II,III,IV	0.127	0.561	.001	30	view →
UCEC	DFS	Median	All	0.931	0.865	.003	18	view →
KIRP	DFS	Median	III,IV	1.000	0.443	.008	18	view →
CHOL	OS	Median	All	0.376	0.845	.006	17	view →
DLBC	DFS	Quartile	All	0.235	0.859	.025	12	view →
SKCM	DFS	Median	IV	0.111	0.694	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

VWA8-AS1–UCS (DFS)

Open the UCS breakdown →