Across TCGA patient cohorts, VWA7 mutation is significantly associated with the RNA expression of many other genes, with 2,985 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VWA7-associated genes across cancer lineages are UHRF1, BCAR1P1, and RNU2-27P. Each is linked with VWA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both VWA7-to-partner and partner-to-VWA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA7→partner) and Y-score (partner→VWA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UHRF1 →	+0.949	+2.818	<.001	<.001	3	3
LIHC	BCAR1P1 →	+0.037	+4.564	<.001	.006	3	3
COAD	RNU2-27P →	+0.835	+3.383	.001	.004	3	3
COAD	RDM1P2 →	+0.091	+4.274	<.001	<.001	3	3
COAD	INO80B-WBP1 →	+0.103	+2.598	<.001	.006	3	3
COAD	SENP3-EIF4A1 →	+0.230	+3.392	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,985 associations by consensus.

Exploration

VWA7 survival (RNA) · tumor vs normal (RNA) · all VWA7 data types