VWA5B2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VWA5B2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,058 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VWA5B2-associated proteins across cancer lineages are UPP1, MYEF2, and MYEF2_S17. Each is linked with VWA5B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both VWA5B2-to-partner and partner-to-VWA5B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA5B2 versus UPP1 in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5B2→partner) and Y-score (partner→VWA5B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMUPP1 →-0.957-0.802<.001<.00134
LSCCMYEF2 →+0.651+0.484<.001<.00134
HNSCMYEF2_S17 →+1.073+0.942<.001.00234
LSCCPPP1R13L →-0.388-0.499<.001.00234
LSCCS100A8 →-1.277-0.657<.001.00234
LSCCSEC24A →-0.313-0.520<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,058 associations by consensus.

VWA5B2 vs UPP1 — GBM

Per-sample scatter of VWA5B2 vs UPP1 in GBM (Pearson r = -0.42).

Explore this scatter interactively →

Exploration