VWA5B1

Across TCGA patient cohorts, VWA5B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,103 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible VWA5B1-associated GO terms across cancer lineages are Organelle disassembly, Negative regulation of gene expression, epigenetic, and Endosomal transport. Each is linked with VWA5B1 in more than 21 cancer types. Because this analysis shows association rather than direction, both VWA5B1-to-partner and partner-to-VWA5B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by VWA5B1-low versus VWA5B1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5B1→partner) and Y-score (partner→VWA5B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Organelle disassembly →	+0.064	+0.357	<.001	<.001	3	20
SCLC	Negative regulation of gene expression, epigenetic →	+0.084	+0.658	<.001	<.001	3	20
SCLC	Endosomal transport →	+0.088	+1.049	<.001	.001	3	20
SCLC	Cytosolic transport →	+0.062	+0.714	<.001	.002	1	22
STAD	Protein localization to vacuole →	+0.063	+0.333	<.001	<.001	3	19
STAD	Establishment of protein localization to vacuole →	+0.060	+0.335	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,103 associations by consensus.

Organelle disassembly by VWA5B1 expression — STAD

Explore this box plot interactively →