VWA5B1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, VWA5B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 517 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible VWA5B1-associated GO terms across cancer lineages are Regulation of dendritic spine maintenance, Primary miRNA processing, and Post-transcriptional gene silencing. Each is linked with VWA5B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both VWA5B1-to-partner and partner-to-VWA5B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendritic spine maintenance grouped by VWA5B1-low versus VWA5B1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5B1→partner) and Y-score (partner→VWA5B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of dendritic spine maintenance →+0.112+0.962.001.00433
LUNG_SCLCPrimary miRNA processing →+0.080+0.975.006.00533
OVARYPost-transcriptional gene silencing →+0.063+0.014.006.00533
UPPER_AERODIGESTIVE_TRACTCOPI-coated vesicle budding →+0.080+0.018.004.00533
UPPER_AERODIGESTIVE_TRACTGolgi transport vesicle coating →+0.080+0.018.004.00533
UPPER_AERODIGESTIVE_TRACTCOPI coating of Golgi vesicle →+0.080+0.018.004.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

Regulation of dendritic spine maintenance by VWA5B1 expression — LUNG_SCLC

Box plot of Regulation of dendritic spine maintenance in VWA5B1-low vs VWA5B1-high samples in LUNG_SCLC.

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Exploration