VWA5A

Across TCGA patient cohorts, VWA5A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,218 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VWA5A-associated proteins across cancer lineages are CHD8_S1995, VWA5A_S639, and PARP4. Each is linked with VWA5A in more than 6 cancer types. Because this analysis shows association rather than direction, both VWA5A-to-partner and partner-to-VWA5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA5A versus CHD8_S1995 in BRCA, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA5A→partner) and Y-score (partner→VWA5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CHD8_S1995 →	-0.428	-1.054	<.001	<.001	3	7
BRCA	VWA5A_S639 →	+1.838	+1.787	.004	.002	3	6
OV	PARP4 →	+0.573	+1.095	<.001	<.001	3	6
OV	MVP →	+0.661	+0.909	<.001	<.001	3	6
GBM	RUFY1 →	+0.221	+0.559	.003	<.001	3	6
BRCA	SIAE →	+0.657	+1.081	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,218 associations by consensus.

VWA5A vs CHD8_S1995 — BRCA

Explore this scatter interactively →