VWA3B

Across TCGA patient cohorts, VWA3B protein abundance is significantly associated with the RNA expression of many other genes, with 5,135 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible VWA3B-associated genes across cancer lineages are KLHDC1, HCAR3, and MEFV. Each is linked with VWA3B in more than 4 cancer types. Because this analysis shows association rather than direction, both VWA3B-to-partner and partner-to-VWA3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VWA3B versus KLHDC1 in BRCA, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VWA3B→partner) and Y-score (partner→VWA3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KLHDC1 →	-1.149	-1.027	<.001	.006	3	5
COAD	HCAR3 →	+2.018	+1.372	<.001	.006	3	5
PDAC	MEFV →	+1.476	+1.955	.004	<.001	3	4
PDAC	SEPTIN4 →	-0.704	-1.400	.001	<.001	3	4
PDAC	IL11RA →	-0.513	-1.224	.001	.004	3	4
PDAC	CXCR1 →	+1.872	+1.811	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,135 associations by consensus.

VWA3B vs KLHDC1 — BRCA

Explore this scatter interactively →