VTI1B

Across TCGA patient cohorts, VTI1B mutation is significantly associated with the RNA expression of many other genes, with 1,009 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VTI1B-associated genes across cancer lineages are VDAC1P3, OR7E156P, and MIR8062. Each is linked with VTI1B in more than 1 cancer types. Because this analysis shows association rather than direction, both VTI1B-to-partner and partner-to-VTI1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VDAC1P3 grouped by VTI1B-low versus VTI1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VTI1B→partner) and Y-score (partner→VTI1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VDAC1P3 →	+0.111	+2.304	.008	<.001	3	2
BRCA	OR7E156P →	+0.796	+5.122	<.001	.008	3	1
BRCA	MIR8062 →	+0.394	+7.471	<.001	.008	3	1
SKCM	RNU6-1131P →	+0.303	+7.816	<.001	.008	3	1
BLCA	RNU6-299P →	+0.210	+5.307	<.001	.001	3	1
BLCA	RN7SL451P →	+0.203	+3.479	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,009 associations by consensus.

VDAC1P3 by VTI1B expression — UCEC

Explore this box plot interactively →