VTI1A

Across TCGA patient cohorts, VTI1A mutation is significantly associated with the RNA expression of many other genes, with 1,049 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VTI1A-associated genes across cancer lineages are RNU6-380P, FAR1P1, and HMGN1P20. Each is linked with VTI1A in more than 2 cancer types. Because this analysis shows association rather than direction, both VTI1A-to-partner and partner-to-VTI1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-380P grouped by VTI1A-low versus VTI1A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VTI1A→partner) and Y-score (partner→VTI1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-380P →	+0.303	+7.816	<.001	.008	3	3
COAD	FAR1P1 →	+0.276	+4.107	<.001	.005	3	2
COAD	HMGN1P20 →	+0.346	+3.910	<.001	.006	3	2
COAD	RN7SL147P →	+0.379	+3.870	.004	.006	3	2
COAD	SNRPCP20 →	+0.613	+5.246	<.001	<.001	3	2
UCEC	RNU6-376P →	+0.249	+3.132	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,049 associations by consensus.

RNU6-380P by VTI1A expression — SKCM

Explore this box plot interactively →