VTCN1

Across TCGA patient cohorts, VTCN1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,278 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VTCN1-associated genes across cancer lineages are RPS15AP9, SPTSSB, and CP. Each is linked with VTCN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both VTCN1-to-partner and partner-to-VTCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VTCN1 versus RPS15AP9 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VTCN1→partner) and Y-score (partner→VTCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS15AP9 →	+0.917	+1.477	.009	<.001	3	5
LUAD	SPTSSB →	+2.558	+2.015	<.001	.001	3	3
LUAD	CP →	+3.453	+1.936	.002	.002	2	4
LUAD	NTN1 →	+1.526	+2.255	.002	.006	3	3
UCEC	PALD1 →	-0.790	-0.730	<.001	.002	3	3
BRCA	GOLPH3 →	+0.447	+1.035	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,278 associations by consensus.

VTCN1 vs RPS15AP9 — HNSC

Explore this scatter interactively →