VTCN1

Across TCGA cell cohorts, VTCN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,438 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible VTCN1-associated GO terms across cancer lineages are Negative regulation of actin filament bundle assembly, Activation of NF-kappaB-inducing kinase activity, and Golgi vesicle transport. Each is linked with VTCN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both VTCN1-to-partner and partner-to-VTCN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament bundle assembly grouped by VTCN1-low versus VTCN1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VTCN1→partner) and Y-score (partner→VTCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of actin filament bundle assembly →	+0.067	+1.054	<.001	.006	2	10
BREAST	Activation of NF-kappaB-inducing kinase activity →	-0.186	-3.268	<.001	<.001	3	9
LARGE_INTESTINE	Golgi vesicle transport →	+0.050	+1.278	<.001	.007	3	8
STOMACH	Positive regulation of GTPase activity →	+0.079	+2.307	<.001	.001	3	8
PANCREAS	Phospholipid biosynthetic process →	+0.034	+0.961	.001	.001	3	8
LUNG_NSCLC_LUAD	Epithelial cell-cell adhesion →	+0.209	+2.004	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Negative regulation of actin filament bundle assembly by VTCN1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →