VTA1

Across TCGA cell cohorts, VTA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,341 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VTA1-associated GO terms across cancer lineages are 7-methylguanosine RNA capping, 7-methylguanosine mRNA capping, and Regulation of sister chromatid segregation. Each is linked with VTA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both VTA1-to-partner and partner-to-VTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine RNA capping grouped by VTA1-low versus VTA1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VTA1→partner) and Y-score (partner→VTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	7-methylguanosine RNA capping →	+0.120	+1.190	.002	.002	3	18
LUNG_NSCLC_LUSC	7-methylguanosine mRNA capping →	+0.120	+1.190	.002	.002	3	18
BREAST	Regulation of sister chromatid segregation →	+0.121	+0.951	<.001	<.001	3	18
LIVER	Ribosomal small subunit export from nucleus →	+0.144	+1.227	.001	.005	3	18
BREAST	Regulation of chromosome segregation →	+0.133	+0.986	<.001	<.001	3	17
BREAST	Regulation of mitotic metaphase/anaphase transition →	+0.126	+0.852	<.001	.003	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

7-methylguanosine RNA capping by VTA1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →