VSX2

Across TCGA patient cohorts, VSX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,939 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VSX2-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Negative regulation of endocytosis, and Establishment of protein localization to membrane. Each is linked with VSX2 in more than 14 cancer types. Because this analysis shows association rather than direction, both VSX2-to-partner and partner-to-VSX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by VSX2-low versus VSX2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VSX2→partner) and Y-score (partner→VSX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nucleoside triphosphate metabolic process →	+0.073	+0.141	.001	.002	3	15
STAD	Negative regulation of endocytosis →	+0.049	+0.082	<.001	<.001	3	15
STAD	Establishment of protein localization to membrane →	+0.060	+0.081	<.001	<.001	3	14
ESCA	Regulation of DNA repair →	+0.059	+0.103	<.001	.003	2	15
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.063	+0.080	<.001	<.001	3	14
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.062	+0.088	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,939 associations by consensus.

Nucleoside triphosphate metabolic process by VSX2 expression — ESCA

Explore this box plot interactively →