VSX2

Across TCGA patient cohorts, VSX2 protein abundance is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSX2-associated genes across cancer lineages are MTHFD2P1, ITM2C, and HMGA1. Each is linked with VSX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VSX2-to-partner and partner-to-VSX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSX2 versus MTHFD2P1 in UCEC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSX2→partner) and Y-score (partner→VSX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTHFD2P1 →	+1.655	+0.250	<.001	.007	3	1
UCEC	ITM2C →	-1.865	-0.250	.005	.007	2	1
UCEC	HMGA1 →	-0.840	-0.250	.009	.007	2	1
UCEC	MUC5AC →	-2.040	-0.250	.007	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

VSX2 vs MTHFD2P1 — UCEC

Explore this scatter interactively →