VSX2

Across TCGA cell cohorts, VSX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 875 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VSX2-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of gene expression, epigenetic, and Protein-DNA complex assembly. Each is linked with VSX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both VSX2-to-partner and partner-to-VSX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by VSX2-low versus VSX2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VSX2→partner) and Y-score (partner→VSX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin formation →	+0.040	+0.012	.005	.005	3	8
OVARY	Negative regulation of gene expression, epigenetic →	+0.067	+0.011	.002	.008	3	7
LUNG_SCLC	Protein-DNA complex assembly →	+0.050	+0.082	<.001	<.001	3	7
LUNG_SCLC	Heterochromatin organization →	+0.042	+0.052	.005	.008	3	6
STOMACH	Regulation of DNA-templated transcription elongation →	+0.087	+0.019	<.001	.007	3	6
STOMACH	Epigenetic regulation of gene expression →	+0.102	+0.033	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 875 associations by consensus.

Heterochromatin formation by VSX2 expression — OVARY

Explore this box plot interactively →