VSX1

Across TCGA cell cohorts, VSX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,368 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VSX1-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Regulation of transcription by RNA polymerase III, and Action potential. Each is linked with VSX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both VSX1-to-partner and partner-to-VSX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical NF-kappaB signal transduction grouped by VSX1-low versus VSX1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VSX1→partner) and Y-score (partner→VSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of canonical NF-kappaB signal transduction →	+0.051	+0.146	<.001	.007	3	4
OVARY	Regulation of transcription by RNA polymerase III →	+0.041	+0.142	.002	.004	3	4
BLOOD_Leukemia	Action potential →	-0.028	-0.192	.004	.005	1	6
LUNG_NSCLC_LUAD	Luteinizing hormone signaling pathway →	+0.835	+0.385	<.001	.008	3	4
LUNG_NSCLC_LUAD	C-terminal protein lipidation →	+0.153	+0.562	<.001	.003	3	4
LUNG_NSCLC_LUSC	Regulation of receptor binding →	-0.306	-0.763	.002	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,368 associations by consensus.

Positive regulation of canonical NF-kappaB signal transduction by VSX1 expression — OVARY

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