VSTM2L

Across TCGA patient cohorts, VSTM2L protein abundance is significantly associated with the RNA expression of many other genes, with 5,053 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VSTM2L-associated genes across cancer lineages are PPL, LYZL4, and CST6. Each is linked with VSTM2L in more than 2 cancer types. Because this analysis shows association rather than direction, both VSTM2L-to-partner and partner-to-VSTM2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSTM2L versus PPL in PDAC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2L→partner) and Y-score (partner→VSTM2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPL →	+0.904	+1.116	<.001	<.001	3	3
BRCA	LYZL4 →	+0.247	+1.142	.002	<.001	3	3
LSCC	CST6 →	+2.689	+1.412	<.001	.002	3	3
LUAD	GTF2IP7 →	+0.721	+1.000	<.001	<.001	3	3
BRCA	CROT →	+1.296	+1.520	<.001	<.001	3	3
BRCA	RPRD1B →	+0.556	+1.396	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,053 associations by consensus.

VSTM2L vs PPL — PDAC

Explore this scatter interactively →