VSTM2L

Across TCGA patient cohorts, VSTM2L mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible VSTM2L-associated genes across cancer lineages are Monocytes, Tregs, and CD4+ T-cells. Each is linked with VSTM2L in more than 1 cancer types. Because this analysis shows association rather than direction, both VSTM2L-to-partner and partner-to-VSTM2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by VSTM2L-low versus VSTM2L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2L→partner) and Y-score (partner→VSTM2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Monocytes →	+0.017	+5.149	<.001	.036	3	1
COAD	Tregs →	+0.061	+4.824	<.001	.045	3	1
COAD	CD4+ T-cells →	+0.037	+6.156	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Monocytes by VSTM2L expression — COAD

Explore this box plot interactively →