VSTM2L

Across TCGA cell cohorts, VSTM2L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,470 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VSTM2L-associated GO terms across cancer lineages are Regulation of macroautophagy, Vesicle budding from membrane, and Respiratory electron transport chain. Each is linked with VSTM2L in more than 8 cancer types. Because this analysis shows association rather than direction, both VSTM2L-to-partner and partner-to-VSTM2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by VSTM2L-low versus VSTM2L-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2L→partner) and Y-score (partner→VSTM2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.049	+1.222	<.001	.008	3	8
LUNG_SCLC	Vesicle budding from membrane →	+0.062	+1.897	.002	<.001	3	8
CNS	Respiratory electron transport chain →	+0.045	+0.941	<.001	<.001	3	8
OESOPHAGUS	Body morphogenesis →	+0.099	+1.557	<.001	<.001	3	7
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.101	+1.926	<.001	.001	2	8
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.983	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,470 associations by consensus.

Regulation of macroautophagy by VSTM2L expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →