Across TCGA patient cohorts, VSTM2B protein abundance is significantly associated with the RNA expression of many other genes, with 3,145 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VSTM2B-associated genes across cancer lineages are LGALS1, SOX10, and SEPTIN3. Each is linked with VSTM2B in more than 1 cancer types. Because this analysis shows association rather than direction, both VSTM2B-to-partner and partner-to-VSTM2B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2B→partner) and Y-score (partner→VSTM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LGALS1 →	-0.745	-0.628	.005	<.001	3	1
GBM	SOX10 →	+1.167	+0.469	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.150	+0.606	<.001	<.001	3	1
GBM	CYP2D6 →	+0.493	+0.361	.007	.009	3	1
GBM	RASL10A →	+0.689	+0.425	<.001	<.001	3	1
GBM	NEFH →	+1.168	+0.543	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,145 associations by consensus.

Exploration

VSTM2B survival (RNA) · tumor vs normal (RNA) · all VSTM2B data types