Across TCGA patient cohorts, VSTM2B mutation is significantly associated with the RNA expression of many other genes, with 705 significant associations in total. COAD shows the largest number of these associations.

The most reproducible VSTM2B-associated genes across cancer lineages are MIR370, KLRC1, and RPS15AP3. Each is linked with VSTM2B in more than 2 cancer types. Because this analysis shows association rather than direction, both VSTM2B-to-partner and partner-to-VSTM2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2B→partner) and Y-score (partner→VSTM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR370 →	+0.356	+3.973	<.001	.008	3	3
COAD	KLRC1 →	+0.341	+3.335	.008	.005	3	2
BRCA	RPS15AP3 →	+0.195	+5.575	<.001	.004	3	2
UCEC	CPNE1 →	-0.649	-2.593	.001	.007	3	2
UCEC	RNA5SP421 →	+0.687	+2.411	<.001	.002	3	2
UCEC	SHLD3 →	+0.524	+2.711	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

Exploration

VSTM2B survival (RNA) · tumor vs normal (RNA) · all VSTM2B data types